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1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride
- CAS No.: 135-87-5
- Purity: 99%
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1.What is the 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride ?
Piperoxan is an α2-adrenergic receptor (α2-AR) antagonist (Kis = 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively) and a first generation histamine receptor antagonist. It reverses decreases in systolic blood pressure induced by clonidine in spontaneously hypertensive rats when administered at a dose of 10 mg/kg.
2.What is the CAS number for 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride ?
The CAS number of 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride is 135-87-5.
3.What are another words for 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride ?
Synonyms?for?1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride 135-87-5:Piperidine,1-(1,4-benzodioxan-2-ylmethyl)-, hydrochloride (8CI); Piperidine,1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-, hydrochloride (9CI); Piperoxanhydrochloride (6CI); 1,4-Benzodioxin, piperidine deriv.;2-(1-Piperidylmethyl)-1,4-benzodioxan hydrochloride;2-Piperidinomethyl-1,4-benzodioxan hydrochloride; 933F hydrochloride; Benodainehydrochloride; Benzodioxane hydrochloride; Compd. 933F; F 933 hydrochloride;Fourneau 933 hydrochloride; Piperoxane hydrochloride; dl-Piperoxanhydrochloride
4.What is 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride (135-87-5) used for?
Used in Pharmaceutical Industry:
1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride is used as a pharmaceutical agent for its potential interaction with α2-adrenergic receptors (α2-ARs). It acts as an antagonist, with Kis values of 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively. This property allows it to reverse the decreases in systolic blood pressure induced by clonidine in spontaneously hypertensive rats when administered at a dose of 10 mg/kg.
Used in Research Applications:
In addition to its potential therapeutic uses, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride can be utilized in research settings to study the effects of α2-AR antagonists on various physiological processes. Its ability to interact with different subtypes of α2-ARs makes it a valuable tool for investigating the roles of these receptors in health and disease.
Used in Drug Development:
The compound's interaction with histamine receptors and its antagonistic properties also make it a candidate for further development as a drug targeting histamine-mediated responses. This could have implications for the treatment of conditions such as allergies, asthma, and other histamine-related disorders.
InChI:InChI=1/C14H19NO2.ClH/c1-4-8-15(9-5-1)10-12-11-16-13-6-2-3-7-14(13)17-12;/h2-3,6-7,12H,1,4-5,8-11H2;1H
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