What is the 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE?

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE is , while it's Molecular Formula is C8H10 O4. 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).

What is the CAS number for 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE?

The CAS number of 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE is 5617-70-9.

What is the 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE?

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE is , while it's Molecular Formula is C8H10 O4. 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).

What is the CAS number for 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE?

The CAS number of 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE is 5617-70-9.

Factory supply 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 5617-70-9 with low price

Q: What is 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE (5617-70-9) used for?

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE is a chemical compound that serves as a crucial reagent in the synthesis of various organic compounds, particularly Bis-benzimidazoles. These Bis-benzimidazoles are known for their inhibitory effects on Type II Dihydrofolate reductase, an enzyme produced by bacteria as a defense mechanism against Trimethoprim.InChI:InChI=1/C8H10O4/c1-7(2)11-5(9)8(3-4-8)6(10)12-7/h3-4H2,1-2H3

Others

Current location:Home > Others

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE

CAS No.:5617-70-9
Purity:99%

Factory supply 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 5617-70-9 with low price

Molecular Formula:C8H10 O4
Molecular Weight:170.165
Vapor Pressure:1.66E-06mmHg at 25°C
Melting Point:63-65 °C(lit.)
Boiling Point:396.8°Cat760mmHg
Flash Point:215.9°C
PSA：52.60000
Density:1.29g/cm³
LogP:0.60270

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(Cas 5617-70-9) Usage

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 7, p. 411, 1990The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030

InChI:InChI=1/C8H10O4/c1-7(2)11-5(9)8(3-4-8)6(10)12-7/h3-4H2,1-2H3

5617-70-9 Relevant articles

Cyclopropylidenemethanone: A Quasi-Symmetrical Molecule

Brown, Ronald D.,Godfrey, Peter D.,Kleiboemer, Burkhard,Champion, Robert,Elmes, Patricia S.

, p. 7715 - 7718 (1984)

The structure of cyclopropylidenemethano...

Preparation method and application of compound containing zinc-bound and quinoline skeleton

-

Paragraph 0139-0142, (2021/11/10)

The invention relates to the field of ph...

Inherent Reactivity of Spiro-Activated Electrophilic Cyclopropanes

Jüstel, Patrick M.,Ofial, Armin R.,Pignot, Cedric D.,Stan, Alexandra

supporting information, p. 15928 - 15935 (2021/10/25)

The kinetics of the ring-opening reactio...

Discovery of novel dual c-Met/HDAC inhibitors as a promising strategy for cancer therapy

Chen, Fei,Dong, Yuhong,Gong, Ping,Hu, Hao,Liu, Yajing

, (2020/06/01)

Owing to the low efficacy and acquired r...

An efficient method for the synthesis of 2′,3′-nonsubstituted cycloalkane-1,3-dione-2-spirocyclopropanes using (2-bromoethyl)-diphenylsulfonium trifluoromethanesulfonate

Nambu, Hisanori,Ono, Naoki,Hirota, Wataru,Fukumoto, Masahiro,Yakura, Takayuki

, p. 1763 - 1768 (2016/12/09)

An efficient and practical synthesis of ...

5617-70-9 Process route

: 598-10-7
cyclopropane-1,1-dicarboxylic acid

: 67-64-1
acetone

: 5617-70-9
cycl-isopropylidene cyclopropane-1,1-dicarboxylate

Conditions

Conditions	Yield
With sulfuric acid; acetic anhydride; at 0 ℃; for 1h;	85%
With sulfuric acid; acetic anhydride; at 30 - 35 ℃;	81.5%
With sulfuric acid; acetic anhydride; at 20 ℃; for 12h; Cooling with ice;	63.2%
With sulfuric acid; acetic anhydride;

: 2033-24-1
cycl-isopropylidene malonate

: 247129-85-7
(2-bromoethyl)(diphenyl)sulfonium trifluoromethanesulfonate

: 5617-70-9
cycl-isopropylidene cyclopropane-1,1-dicarboxylate

Conditions

Conditions	Yield
With potassium carbonate; In ethyl acetate; at 20 ℃; for 2h;	80%

5617-70-9 Upstream products

598-10-7
cyclopropane-1,1-dicarboxylic acid
67-64-1
acetone
505048-26-0
5-(2-chloroethyl)-2,2-dimethyl-1,3-dioxane-4,6-dione
2033-24-1
cycl-isopropylidene malonate

5617-70-9 Downstream products

98207-69-3
dimethyl 2-(2-chloro-3-p-toluenesulfonylpyrrol-1-yl)methylmalonate
80965-17-9
C₁₉H₁₆Br₂NO₅^(1-)*Na⁽¹⁺⁾
53917-46-7
N^ε-(benzyloxycarbonyl)-N^α-formyllysine methyl ester
97551-29-6
6-<(benzyloxycarbonyl)amino>-2(S)-(3-carboxy-2-oxo-1-pyrrolidinyl)hexanoic acid methyl ester